Lucy Penelope Gwynn, the first woman registrar of Trinity College Dublin (TCD), is born in County Donegal on September 22, 1865.

Gwynn’s father, John Gwynn, is a Syriacist and Regius Professor of Divinity at TCD. Her mother is Lucy O’Brien, daughter of MP William Smith O’Brien. Her eight brothers include the author and politician Stephen Gwynn, the academic Edward Gwynn, the career soldier Major General Sir Charles Gwynn, the cricketers Lucius Gwynn and Arthur Gwynn, the academic cleric and social reformer Robert (Robin) Gwynn, the Indian civil servant and journalist John Tudor (Jack) Gwynn and the Irish civil servant Brian Gwynn. She has one sister, Mary Gwynn, the wife of Henry Bowen and stepmother of the writer Elizabeth Bowen. She is a niece of Harriet Monsell.

Gwynn is appointed first lady registrar of Trinity College Dublin in February 1905. Women had only been admitted to the university the previous year. Despite coming from a family of academics, she had been unable to get a university education herself. She is 39 years old when appointed to her position in the university.

Students describe Gwynn as a pioneer. Her role as women’s registrar is described by one of her charges as “to control our movements to some extent and to protect the college and the students from criticism.”

In 1907, Gwynn is summoned before the Fry Commission on Dublin University to defend the position of women at Trinity. She is supported by the parents of the students. The result is that the commission endorses the principle of women’s admission to the university.

In 1922, the Dublin University Women Graduates’ Association is founded, under Gwynn’s presidency.

Gwynn never marries. As an eldest daughter she is required to assist in the management of her parents’ household and attend to them in their old age. From her mother’s brother, architect Robert Donough O’Brien, she inherits the house he had designed and built at Parteen-a-Lax in County Clare, close to Limerick. It is there that she retires at the end of her working life. Her hobby is tending its beautiful garden which lay next to the River Shannon.

Gwynn dies in County Clare in 1947.

Founded, by subscription, in 1948 in memory of Lucy Gwynn, the Lucy Gwynn Memorial Prize is awarded annually in the Michaelmas term to a Junior Sophister woman student for distinction in her course. The award is made by two women on the university staff nominated by the Board, and one of the female tutors. The value of the prize is €1,207.